为什么李森科的学说会得到政治支持?

李森科那一套是传承自拉马克的“获得性遗传学”,目前叫做表观遗传学epigenomic。表观遗传就是呈现出“用进废退”特征的遗传现象,与DNA甲基化...


16 篇 Nature 重磅发布大脑运动皮层细胞图谱,有怎样的...

Epigenomic diversity of cortical projection neurons in the mouse brain。该工作利用逆行标记和单个核DNA甲基化测序,检测了63个皮质-皮层、皮质...


胶质瘤文献1:脑干胶质瘤的整合基因组和表观基因组图谱 - 百度...

标题:The integrated genomic and epigenomic landscape of brainstem glioma 期刊:nature communications 影响因子:14.912 发表时间:2020 摘要 脑干胶质瘤是一组异质性肿瘤...


组学技术——ATAC - seq

Zaba LC, Chang HY, Greenleaf WJ. Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin,


ATAC - seq经典之作

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position: https://www.nature.com...


人类对大脑的的研究到了哪个水平?

研究二:A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex。构建小鼠初级运动皮层中超过50万个细胞的单细胞转录组...


ChIP - seq需知问题及展望

Zhang, A. He, CoBATCH forHigh-Throughput Single-Cell Epigenomic Profiling, Mol Cell 76(1) (2019) 206-216e7. [26] A. Harada, K. Maehara,T. Handa, Y. Arimura, ...


文献阅读笔记:CUT&Tag

CUT&Tag for efficient epigenomic profiling of small samples and single cells 许多染色质特征在调控基因表达中起着重要作用。要完全理解基因调控,需要在小样本细胞中以高分辨率绘制...


组学技术—— CUT&Tag

References [1] Kaya-Okur, Hatice S et al. CUT&Tag for efficient epigenomic profiling of small samples and single cells. Nature communications vol. 10...


Harvard FAS Informatics出品的ATAC - seq测序指南

Buenrostro JD, Giresi PG, Zaba LC, Chang HY, Greenleaf WJ. Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-...


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